Wednesday, October 14, 2009

Obesity is NOT A Joke!!!

Obesity is not only change your body shape. It also will affect your body system. It might bring serious consequences in your life if you ignore this.

Case 1: Obesity versus Type 2 Diabetes Mellitus
Obesity will cause risk to type 2 diabetes mellitus. According to the researches, large populations of diabetes sufferers are caused by obesity. There is a connection between obesity and insulin resistance.

Type 2 diabetes mellitus is characterized by high blood glucose due to insulin resistance and relative insulin deficiency. Insulin is a hormone which takes up glucose from the blood, storing it as glycogen in the liver and muscle, and stopping use of fat as an energy source. Insulin resistance means that body cells do not give respond when insulin is present. Therefore, it results in excessive amount of glucose in blood, called hypergycaemia. It might lead to kidney disease and blindness.

Case 2: Obesity versus Hormonal Metabolic Imbalance
Obesity also has close relationship with leptin resistance. Leptin is a hormone to regulate body’s energy input and outout by controlling food intake. Normally, if the person is weight loss, leptin amount will decrease to increase the appetite and slow down the metabolism; while if the person is weight gain, leptim amount will increase to decrease the appetite and increase the body metabolism. However, leptin resistance is caused by the body do not give response to the presence of leptin hormone. Therefore, if the people are weight gain, leptin hormone does not function very well, the appetite still increase and the metabolism is stay low, so the people will continue gain weight, causes obesity.

Case 3: Obesity versus Impaired Glucose Tolerance
Obesity and impaired glucose tolerance are closely interlinked. Impaired glucose tolerance (IGT) is a sign of insulin resistance and decreased metabolic capacity. According to the reports, if IGT is reversed, the BMI in overweight or obese people will be reduced.

Case 4: Obesity versus Breast, Prostate and Colorectal Cancers
Hormone-related cancers such as breast and prostate neoplasia are closely associated with obesity. Due to obesity is having a fat-rich diet, it will cause high risk of development in large bowel tumor growth which called colorectal cancer. In women, obesity and insulin resistance might lead to polycystic ovary syndrome and infertility.

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